As the recent election proved and as others have proven in the past, states are entities with minds of their own. So when there is a seemingly national trend, there are still those states that stand out as different and notable in regards to certain matters. California tends to stand out for various reasons.
Today's society provides a sense that business can be the big bad wolf. But that is simply not true. Businesses keep an economy strong. They keep people employed and able to support their families. The strength of corporate America can symbolize an overall strength of the country.
Marijuana is still a Schedule I controlled substance under federal law, and the passage of Prop 64 by California voters will not change that. Nevertheless, the legalization of cannabis for recreational purposes is likely to remove some of the stigma around weed in general, which may make doctors more open to its use in conditions that aren't currently on the list.